Fabrication of nanocrystal forms of ᴅ-cycloserine and their application for transdermal and enteric drug delivery systems

• Hsuan-Ang Tsai,
• Tsai-Miao Shih,
• Theodore Tsai,
• Jhe-Wei Hu,
• Yi-An Lai,
• Jui-Fu Hsiao and
• Guochuan Emil Tsai

Beilstein J. Nanotechnol. 2024, 15, 465–474, doi:10.3762/bjnano.15.42

• absorber [20]. In addition, silver (Ag) nanoparticles were synthesized from cotton fabrics and exhibited strong inhibition activity against some bacteria [21]. Recently, pure active pharmaceutical ingredient (API) composed of nanocrystals was investigated, as opposed to drug nanocarrier platforms [22

Influence of conductive carbon and MnCo₂O₄ on morphological and electrical properties of hydrogels for electrochemical energy conversion

• Sylwia Pawłowska,
• Karolina Cysewska,
• Yasamin Ziai,
• Jakub Karczewski,
• Piotr Jasiński and
• Sebastian Molin

Beilstein J. Nanotechnol. 2024, 15, 57–70, doi:10.3762/bjnano.15.6

• ]. Cai et al. found some silver nanoparticles only slightly present in the skeleton of a PVA@DEL composite hydrogel [23]. Most of the Ag nanoparticles were observed in the wall of the hydrogel network. In our case, for the Hgel-MCO-cCB 1:3 sample, when the volume percentage of cCB was 17.1% (Table 3

Silver-based SERS substrates fabricated using a 3D printed microfluidic device

• Phommachith Sonexai,
• Minh Van Nguyen,
• Bui The Huy and
• Yong-Ill Lee

Beilstein J. Nanotechnol. 2023, 14, 793–803, doi:10.3762/bjnano.14.65

• tool for detecting ultralow concentrations of chemical compounds and biomolecules. We present a reproducible method for producing Ag nanoparticles that can be used to create highly sensitive SERS substrates. A microfluidic device was employed to confine the precursor reagents within the droplets

• , resulting in Ag nanoparticles of uniform shape and size. The study investigates the effects of various synthesis conditions on the size distribution, dispersity, and localized surface plasmon resonance wavelength of the Ag nanoparticles. To create the SERS substrate, the as-synthesized Ag nanoparticles were

• aqueous solutions and oil, respectively. Synthesis of silver nanoparticles Different molar ratios of silver nitrate to sodium borohydride were used to produce Ag nanoparticles in the microfluidic device at room temperature, with flow rates of 20 and 80 µL/min for the aqueous solutions and oil

Metal-organic framework-based nanomaterials as opto-electrochemical sensors for the detection of antibiotics and hormones: A review

• Akeem Adeyemi Oladipo,
• Saba Derakhshan Oskouei and
• Mustafa Gazi

Beilstein J. Nanotechnol. 2023, 14, 631–673, doi:10.3762/bjnano.14.52

• improved electrochemical performance [63][67]. In a recent study, Tang et al. [29] used an ultrasonication and reduction process to combine nanostructured Ag nanoparticles with a MOF (ZIF-67) to fabricate nanopinna-based composite electrochemical sensors for acetaminophen detection. The results showed a

• wide linear detection range with a detection limit of 0.05 μM. Due to the synergistic effects of the wide porosity and high specific surface area of the MOF and the outstanding catalytic activity and high conductivity of Ag nanoparticles, the hybridisation improved the electrochemical performance of

SERS performance of GaN/Ag substrates fabricated by Ag coating of GaN platforms

• Magdalena A. Zając,
• Bogusław Budner,
• Malwina Liszewska,
• Bartosz Bartosewicz,
• Łukasz Gutowski,
• Jan L. Weyher and
• Bartłomiej J. Jankiewicz

Beilstein J. Nanotechnol. 2023, 14, 552–564, doi:10.3762/bjnano.14.46

• to the platform’s surface. The dimensions of these nanoparticles increase with the temperature of the GaN substrate up to 200 °C, and, consequently, their number decreases. The largest Ag nanoparticles reach a diameter of 150–170 nm in the case of the PLD_1_200 sample. An increase in temperature also

• leads to an increase in the degree of crystallization of these Ag nanoparticles. At a temperature of 400 °C, more cubic and better crystallized nanoparticles are visible in the SEM images, but their dimensions are smaller than at 200 °C (Figure 4). The thermodynamic conditions of the Ag layer formation

• favor the crystallization and growth of Ag nanoparticles on the surface of the pillars and at the ends of the spiky structures surrounding them. The Ag nanoparticles formed at the ends of the spiky structures are located at small distances from each other or even coalesce. As a result, a porous, well

Plasmonic nanotechnology for photothermal applications – an evaluation

• A. R. Indhu,
• L. Keerthana and
• Gnanaprakash Dharmalingam

Beilstein J. Nanotechnol. 2023, 14, 380–419, doi:10.3762/bjnano.14.33

• extinction spectra of nanostructures. Illustrative examples of the absorbance spectra for different morphologies of Ag nanoparticles are shown in Figure 2, elucidating the influence of the same. The extinction spectra (the summation of absorption and scattering spectra) from which the shape effects of

Quercetin- and caffeic acid-functionalized chitosan-capped colloidal silver nanoparticles: one-pot synthesis, characterization, and anticancer and antibacterial activities

• Akif Hakan Kurt,
• Elif Berna Olutas,
• Fatma Avcioglu,
• Hamza Karakuş,
• Mehmet Ali Sungur,
• Cansu Kara Oztabag and
• Muhammet Yıldırım

Beilstein J. Nanotechnol. 2023, 14, 362–376, doi:10.3762/bjnano.14.31

• NPs is higher in U-118 MG cells than in ARPE-19 cells at the same concentrations. The quercetin-containing Ag nanoparticles (Ch/Q-Ag NPs) may be accepted as a candidate for use in cancer treatment. Furthermore, the concentration-dependent cell death caused by Ch/CA-Ag NPs in U-118 MG cells is

Combining physical vapor deposition structuration with dealloying for the creation of a highly efficient SERS platform

• Adrien Chauvin,
• Walter Puglisi,
• Damien Thiry,
• Cristina Satriano,
• Rony Snyders and
• Carla Bittencourt

Beilstein J. Nanotechnol. 2023, 14, 83–94, doi:10.3762/bjnano.14.10

• efficiency compared to that of Au, Ag nanoparticles (NPs) are prone to oxidation. Moreover, they are less thermodynamically stable leading to morphology variation and ultimately to deterioration of their SERS efficiency [13][14]. Besides that, most studies report on the high SERS properties for NPs in

In search of cytotoxic selectivity on cancer cells with biogenically synthesized Ag/AgCl nanoparticles

• Mitzi J. Ramírez-Hernández,
• Mario Valera-Zaragoza,
• Omar Viñas-Bravo,
• Ariana A. Huerta-Heredia,
• Miguel A. Peña-Rico,
• Erick A. Juarez-Arellano,
• David Paniagua-Vega,
• Eduardo Ramírez-Vargas and
• Saúl Sánchez-Valdes

Beilstein J. Nanotechnol. 2022, 13, 1505–1519, doi:10.3762/bjnano.13.124

• the obtaining of metallic Ag nanoparticles combined with AgCl, where AgNPs were formed by reducing compounds of the extract. Thus, the formation of AgCl was due to the availability of chlorine salts in pineapple peels. The third novelty shown in this work is that the cytotoxic activity of Ag/AgCl

• ] these color changes were also observed during the formation of AgNPs from the Stevia rebaudiana extract. This behavior was attributed to the gradual formation of Ag nanoparticles, and the morphological changes that occur during biosynthesis. It is important to note that temperature has a considerable

• compounds act as reducing agents, as well as to changes in the shape, size, and size distribution of the resulting Ag nanoparticles. Cytotoxic behavior It has been reported that several cytotoxic mechanisms of AgNPs can cause DNA, mitochondrial, and cell membrane damage as well as apoptosis [44]. Here, the

Design of surface nanostructures for chirality sensing based on quartz crystal microbalance

• Yinglin Ma,
• Xiangyun Xiao and
• Qingmin Ji

Beilstein J. Nanotechnol. 2022, 13, 1201–1219, doi:10.3762/bjnano.13.100

• nanoparticles [124]. Zhang et al. used ʟ-cysteine modified Au nanoparticles for chiral recognition of carnitine [125]. Jafari et al. used chitosan modified Ag nanoparticles for chiral sensing of tryptophan enantiomers [126]. Niu et al. reported the chiral recognition of tryptophan (Trp) on chiral Au facets

• of metal-based chiral sensing applications. Based on surface modification or induced crystallization, metal nanostructures may bear chiral surfaces for chiral sensing of enantiomers. For example, Zhang et al. achieved chiral recognition of cysteine enantiomers using nucleotide-modified Ag

Zinc oxide nanostructures for fluorescence and Raman signal enhancement: a review

• Ioana Marica,
• Fran Nekvapil,
• Maria Ștefan,
• Cosmin Farcău and
• Alexandra Falamaș

Beilstein J. Nanotechnol. 2022, 13, 472–490, doi:10.3762/bjnano.13.40

• also benefits the SERS enhancement. Doping zinc oxide–Ag nanoparticles with magnesium also introduces defect sites (surface defects and oxygen vacancies), which form new energy levels below the conduction band of zinc oxide, facilitating the charge transfer mechanism. In this case, besides the charge

A comprehensive review on electrospun nanohybrid membranes for wastewater treatment

• Senuri Kumarage,
• Imalka Munaweera and
• Nilwala Kottegoda

Beilstein J. Nanotechnol. 2022, 13, 137–159, doi:10.3762/bjnano.13.10

Self-assembly of amino acids toward functional biomaterials

• Huan Ren,
• Lifang Wu,
• Lina Tan,
• Yanni Bao,
• Yuchen Ma,
• Yong Jin and
• Qianli Zou

Beilstein J. Nanotechnol. 2021, 12, 1140–1150, doi:10.3762/bjnano.12.85

• nanoparticles (Ag NPs) hold great promise due to their broad-spectrum and robust antimicrobial properties [65]. The main mechanism is that Ag nanoparticles diffuse into cells and destroy cell walls [66]. However, Ag NPs are cytotoxic, which limits their application [67]. Song et al. [68] developed a broad

High-yield synthesis of silver nanowires for transparent conducting PET films

• Gul Naz,
• Hafsa Asghar,
• Muhammad Ramzan,
• Muhammad Arshad,
• Rashid Ahmed,
• Muhammad Bilal Tahir,
• Bakhtiar Ul Haq,
• Nadeem Baig and
• Junaid Jalil

Beilstein J. Nanotechnol. 2021, 12, 624–632, doi:10.3762/bjnano.12.51

• reaction temperature of 160 °C, the AgNO3/PVP ratio has also great effect on the morphology of AgNWs [53]. In our case, a 1:1 ratio of AgNO3/PVP started the growth of Ag nanoparticles, as can be seen in the SEM image in Figure 4a. Adding more PVP to the reaction promotes the formation of AgNWs. A AgNO3/PVP

On the stability of microwave-fabricated SERS substrates – chemical and morphological considerations

• Limin Wang,
• Aisha Adebola Womiloju,
• Christiane Höppener,
• Ulrich S. Schubert and
• Stephanie Hoeppener

Beilstein J. Nanotechnol. 2021, 12, 541–551, doi:10.3762/bjnano.12.44

• additives to fabricate uniform Ag nanoparticles. These include basic aminoacids (such as ʟ-lysine or ʟ-arginine) and soluble starch or other additives, which act as reducing and protecting agents, respectively [22]. In our approach, the monolayer of silver nanoparticles is formed by the reduction of silver

• process. All substrates were characterized before the stability tests and revealed the formation of a reproducible monolayer of nanoparticles on the substrate, which is in line with the previously reported procedure. Typically, the Ag nanoparticles synthesized by the microwave-assisted synthesis approach

• might be related to the fact that the irregularly shaped Ag nanoparticles can be reshaped into more spherical nanoparticles after immersion into ethanol [30]. An evidence for this effect can be found in Figure S3 since after 4 h of immersion into ethanol more spherical nanoparticles were observed. The

Nickel nanoparticle-decorated reduced graphene oxide/WO₃ nanocomposite – a promising candidate for gas sensing

• Ilka Simon,
• Alexandr Savitsky,
• Rolf Mülhaupt,
• Vladimir Pankov and
• Christoph Janiak

Beilstein J. Nanotechnol. 2021, 12, 343–353, doi:10.3762/bjnano.12.28

• [42]. With the addition of Ag nanoparticles to a dispersion of SnO2/rGO, the working temperature was dropped from 55 °C to room temperature in the gas sensing of NO2 [43]. (For further examples and comparison with other gas sensors see Table S1 in Supporting Information File 1.) The ternary Ni@rGO/WO3

Oxidation of Au/Ag films by oxygen plasma: phase separation and generation of nanoporosity

• Abdel-Aziz El Mel,
• Said A. Mansour,
• Mujaheed Pasha,
• Atef Zekri,
• Janarthanan Ponraj,
• Akshath Shetty and
• Yousef Haik

Beilstein J. Nanotechnol. 2020, 11, 1608–1614, doi:10.3762/bjnano.11.143

• a fundamental point of view, gold/silver is a peculiar model system to study corrosion processes since gold is a noble metal. Interestingly, by using different types of Au/Ag nanoparticles, Lewis et al. showed how one can control and engineer, at the nanometer scale, the final shape and structure of

Antimicrobial metal-based nanoparticles: a review on their synthesis, types and antimicrobial action

• Matías Guerrero Correa,
• Fernanda B. Martínez,
• Cristian Patiño Vidal,
• Camilo Streitt,
• Juan Escrig and
• Carol Lopez de Dicastillo

Beilstein J. Nanotechnol. 2020, 11, 1450–1469, doi:10.3762/bjnano.11.129

• -condensation of the vapors on the cold surface of the vacuum reactor. Sergeev et al. [45] obtained Ag nanoparticles with sizes ranging from 20 to 150 nm using this technique. The electrochemical anodization method is based on the reactions that occur between the electrode and the electrolyte. In this method

• addition, with this technique one can control the morphology of the synthesized nanoparticles. For example, while Johans et al. [46] obtained spherical Ag nanoparticles, Galstyan et al. [47] synthesized nanoparticles in the form of elongated aggregates with a chain-like morphology. The hydrolysis technique

Ultrasensitive detection of cadmium ions using a microcantilever-based piezoresistive sensor for groundwater

• Dinesh Rotake,
• Anand Darji and
• Nitin Kale

Beilstein J. Nanotechnol. 2020, 11, 1242–1253, doi:10.3762/bjnano.11.108

• . Results of the SAM detecting cadmium ions The proposed microfluidic platform provides real-time monitoring of Cd(II) in groundwater. We performed the experiment using the coating of cysteamine thiol with cross-linked ᴅʟ-glyceraldehyde (Cys-DL-GC). We have already discussed that the methods based on Au/Ag

• nanoparticles require the laboratory equipment such as fluorescence spectroscopy, which ultimately leads to a non-portable platform. Hence, our primary focus is the selective detection of the Cd(II) using the fabricated portable experimental platform. We used the following experimental procedure. A stock

Photothermally active nanoparticles as a promising tool for eliminating bacteria and biofilms

• Mykola Borzenkov,
• Piersandro Pallavicini,
• Angelo Taglietti,
• Laura D’Alfonso,
• Maddalena Collini and
• Giuseppe Chirico

Beilstein J. Nanotechnol. 2020, 11, 1134–1146, doi:10.3762/bjnano.11.98

• formation are controversial as the Ag nanoparticles seem to be effective against the Gram-negative but not so much against the Gram-positive strains [6]. The antibacterial properties of a wide range of nanoparticles and their corresponding nanocomposites, such as ZnO [17][18], TiO2 [19][20], Fe3O4 [21][22

Gram-scale synthesis of splat-shaped Ag–TiO₂ nanocomposites for enhanced antimicrobial properties

• Mohammad Jaber,
• Asim Mushtaq,
• Kebiao Zhang,
• Jindan Wu,
• Dandan Luo,
• Zihan Yi,
• M. Zubair Iqbal and
• Xiangdong Kong

Beilstein J. Nanotechnol. 2020, 11, 1119–1125, doi:10.3762/bjnano.11.96

• decrease in the crystallinity and the appearance of new peaks were observed when the Ag nanoparticles were added. The additional peaks corresponded to Ag at 2θ values of 36.78(103), which is perfectly indexed with the silver lattice planes (JCPDS 04-0783). Importantly, no impurity peaks were observed in

• interactions. In addition, the PVP also acted as a reducing agent and facilitated the formation of small Ag nanoparticles at the surface of the TiO2 spheres to form a splat-shaped structure (Scheme 1). PVP played a significant role in generating these nanocomposites, serving as a growth modifier, stabilizer

• the antibacterial activity. The aim of this study was to improve the antimicrobial activity of the biocompatible TiO2 material by growing the small Ag nanoparticles onto its surface. It is known that the Ag free radicals are used to kill bacteria due to their highly oxidative nature; however, when

Effect of Ag loading position on the photocatalytic performance of TiO₂ nanocolumn arrays

• Jinghan Xu,
• Yanqi Liu and
• Yan Zhao

Beilstein J. Nanotechnol. 2020, 11, 717–728, doi:10.3762/bjnano.11.59

• volume unchanged. Results and Discussion Figure 1 depicts a schematic diagram of the preparation process of the ACT and AFT nanocolumn arrays (schemes (1) and (2), respectively). In the structure represented in (2), the bottom of the array hinders the dense accumulation of Ag nanoparticles in the

• nanocolums or the formation of agglomerates. Instead, the Ag-filled TiO2 nanocolumn structure (2) is obtained. On the other hand, the Ag-coated structure (1) is formed without the hindrance of the bottom structure, in which the Ag nanoparticles deposit more densely and form larger nanoparticles. The

• Ag deposition thicknesses of 10, 20, and 40 nm, respectively. We can see that, as the thickness of Ag deposition increases, the array of TiO2 is gradually covered until the nanocolumn structure disappears. To observe the distribution of Ag nanoparticles in the AFT nanocolumn array, the AAO template

Silver-decorated gel-shell nanobeads: physicochemical characterization and evaluation of antibacterial properties

• Marta Bartel,
• Katarzyna Markowska,
• Marcin Strawski,
• Krystyna Wolska and
• Maciej Mazur

Beilstein J. Nanotechnol. 2020, 11, 620–630, doi:10.3762/bjnano.11.49

• nanoparticles. This approach is similar in some aspects to synthetic strategies reported in the literature. For example, Li et al. [41] proposed the decoration of the surface of polystyrene microspheres with silver nanoparticles through adsorption (the Ag nanoparticles were generated in the solution through

• composite particles (the Ag nanoparticles are coordinated to thiol groups generated in situ during the synthesis), in a simple and relatively fast reaction. Antibacterial activity of PSSAg nanocomposite We were further interested whether the silver-modified beads show antibacterial effects. To determine the

• silver nanoparticles. Radzig and co-workers observed that Ag nanoparticles of 8.3 ± 1.9 nm in size hamper the biofilm formation of E. coli and P. aeruginosa. The reduction of bacterial biomass in the biofilm was visible when the concentration was higher than 5 μg/mL for E. coli and 10 μg/mL for P

Evolution of Ag nanostructures created from thin films: UV–vis absorption and its theoretical predictions

• Robert Kozioł,
• Marcin Łapiński,
• Paweł Syty,
• Damian Koszelow,
• Wojciech Sadowski,
• Józef E. Sienkiewicz and
• Barbara Kościelska

Beilstein J. Nanotechnol. 2020, 11, 494–507, doi:10.3762/bjnano.11.40

• appears around 350 nm, which probably corresponds to the quadrupole resonance. For calculations leading to a better illustration of absorption, scattering and overall absorption of light in Ag nanoparticles, the Mie theory is employed. Absorbance and the distribution of the electromagnetic field around

• nanostructures, in which LSPR occurs in the visible spectrum. The frequency of LSPR depends on the size and shape of the nanostructures and the dielectric function of the surrounding medium [6][7][8]. Regarding a potential implementation, Ag nanoparticles are especially interesting because of their very high

• extinction cross section. It can be up to 50 times larger than the geometrical cross section of the nanoparticle [6]. Ag nanoparticles are also interesting because of the position of the plasmon resonance. The LSPR wavelength maximum of small Ag nanoparticles with a diameter of 10 nm in air is around 420 nm

Nanoparticles based on the zwitterionic pillar[5]arene and Ag⁺: synthesis, self-assembly and cytotoxicity in the human lung cancer cell line A549

• Dmitriy N. Shurpik,
• Denis A. Sevastyanov,
• Pavel V. Zelenikhin,
• Pavel L. Padnya,
• Vladimir G. Evtugyn,
• Yuriy N. Osin and
• Ivan I. Stoikov

Beilstein J. Nanotechnol. 2020, 11, 421–431, doi:10.3762/bjnano.11.33

• University, 420008 Kremlevskaya, 18, Kazan, Russian Federation Interdisciplinary Centre for Analytical Microscopy, Kazan Federal University, 420008 Kazan, Kremlevskaya 18, Russian Federation 10.3762/bjnano.11.33 Abstract For the first time, stable pillar[5]arene/Ag+ nanoparticles, consisting of water

•  1, Table S3). Figure 4 shows that the diffusion coefficients for pillar[5]arene 3 and 3/Ag+ nanoparticles are different. The self-diffusion coefficient of pillar[5]arene 3 is greater (D = 4.22 × 10–10 m2 s−1), which indicates its greater mobility in solution in comparison with 3/Ag+ associates. This

• pronounced toxic effect in the range of studied concentrations of 10–500 μg/mL [44][45][46]. In order to study the cytotoxic properties of the obtained 3/Ag+ nanoparticles, we evaluated the cytotoxicity of the synthesized water-soluble pillar[5]arenes 3 and 4. The results indicate that macrocycles 3 and 4